Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329275 | 1.00 | DPP7 (0.55) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL4970721 | 0.98 | DPP7 (0.53) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL29996821 | 0.95 | DPP7 (0.50) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL28895832 | 0.80 | DPP7 (0.40) | DPP7GAALMNAKMT2AMEN1 | |
| SCHEMBL1428600 | 0.80 | DPP7 (0.45) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL3721003 | 0.75 | DPP7 (0.41) | DPP7GAALMNAFDPSALDH1A1 | |
| SCHEMBL23822377 | 0.75 | SLC7A5 (0.36) | DPP7KMT2AMEN1CYP2D6KCNH2 | |
| SCHEMBL11687527 | 0.74 | DPP7 (0.48) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL26986914 | 0.74 | DPP7 (0.48) | DPP7GAALMNAFDPSCYP1A2 | |
| SCHEMBL3969170 | 0.74 | DPP7 (0.48) | DPP7GAALMNAFDPSCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933288-B2 | Pyranosyl cytosines: pharmaceutical formulations and methods | ISIS PHARMACEUTICALS, INC. | 2005-08-23 | — | — | US | disclosed |