Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279338 | 0.84 | CYP1A2 (0.38) | TP53THRBCYP1A2MAPTALDH1A1 | |
| SCHEMBL5067602 | 0.80 | CYP1A2 (0.42) | CYP1A2MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL17984648 | 0.75 | CYP1A2 (0.50) | TP53THRBCYP1A2MAPTALDH1A1 | |
| SCHEMBL5067600 | 0.72 | POLB (0.42) | CYP1A2ALDH1A1LMNAKMT2ARAD52 | |
| SCHEMBL5642066 | 0.71 | CYP1A2 (0.64) | CYP1A2MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL1645260 | 0.69 | CYP1A2 (0.56) | TP53CYP1A2MAPTALDH1A1LMNA | |
| SCHEMBL30831836 | 0.67 | CYP1A2 (0.51) | CYP1A2MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4040622 | 0.67 | CYP1A2 (0.41) | TP53THRBCYP1A2MAPTALDH1A1 | |
| SCHEMBL2473041 | 0.66 | CYP1A2 (0.53) | CYP1A2MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL13197220 | 0.66 | CYP1A2 (0.56) | CYP1A2MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |