Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.54 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7313025 | 0.98 | HPGD (0.55) | HPGDHTTALDH1A1TSHRUSP2 | |
| Hydrochloric Acid SCHEMBL9742136 | 0.98 | HPGD (0.55) | HPGDHTTALDH1A1TSHRUSP2 | |
| Bromide SCHEMBL15106751 | 0.98 | HPGD (0.55) | HPGDHTTALDH1A1TSHRUSP2 | |
| SCHEMBL64895 | 0.94 | HPGD (0.51) | HPGDHTTALDH1A1TSHRUSP2 | |
| SCHEMBL20188098 | 0.89 | HPGD (0.65) | HPGDHTTALDH1A1TSHRHSP90AA1 | |
| SCHEMBL22015905 | 0.89 | HPGD (0.65) | HPGDHTTALDH1A1TSHRHSP90AA1 | |
| Tert-Butyl Formate SCHEMBL27911780 | 0.89 | HPGD (0.46) | HPGDHTTALDH1A1TSHRUSP2 | |
| SCHEMBL3918577 | 0.86 | TSHR (0.56) | HPGDALDH1A1TSHRUSP2HSD17B10 | |
| SCHEMBL3898465 | 0.86 | HPGD (0.61) | HPGDHTTALDH1A1TSHRHSD17B10 | |
| SCHEMBL28242074 | 0.86 | HPGD (0.61) | HPGDHTTALDH1A1TSHRHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 509 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131792-B | Process for preparation of apoptosis promoter ABT-263 | ABBOTT LAB | 2014-05-07 | — | — | CN | claimed |
| EP-2307393-B1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | ABBOTT LAB (US) | 2013-04-10 | — | — | EP | claimed |
| US-8168784-B2 | Processes to make apoptosis promoters | ABBOTT LABORATORIES (US) | 2012-05-01 | — | — | US | claimed |
| US-8084607-B2 | Apoptosis promoters | ABBOTT LABORATORIES (US) | 2011-12-27 | — | — | US | claimed |
| JP-2011525182-A | — | — | 2011-09-15 | — | — | JP | claimed |
| CN-102131792-A | Process for preparation of apoptosis promoter abt-263 | ABBOTT LAB | 2011-07-20 | — | — | CN | claimed |
| EP-2307393-A1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | Abbott Laboratories (US) | 2011-04-13 | — | — | EP | claimed |
| US-20100022773-A1 | APOPTOSIS PROMOTERS | ABBVIE INC. | 2010-01-28 | — | — | US | claimed |
| US-20090318689-A1 | Processes To Make Apoptosis Promoters | ABBOTT LABORATORIES (US) | 2009-12-24 | — | — | US | claimed |
| WO-2009155386-A1 | A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 | ABBOTT LABORATORIES (US) | 2009-12-23 | — | — | WO | claimed |
| EP-4743446-A1 | NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA | Board of Trustees of Michigan State University (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS INC (US) | 2026-04-02 | — | — | US | disclosed |
| US-20260014147-A1 | STAT6 DEGRADERS | GILEAD SCIENCES INC (US) | 2026-01-15 | — | — | US | disclosed |
| US-20260001893-A1 | SMALL MOLECULE MODULATORS OF STAT6 | GILEAD SCIENCES INC (US) | 2026-01-01 | — | — | US | disclosed |
| EP-4667469-A1 | COMPOUND CONTAINING TRIFLUOROMETHYLSULFONYL | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2025-12-24 | — | — | EP | disclosed |
| US-4882330-A | 1-aryloxy-4-[((4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-11-21 | — | — | US | disclosed |
| EP-0269383-A2 | 1-Aryloxy-4-[(4-aryl)-1-piperazinyl]-2-butanols useful as antiallergy agents | A.H. ROBINS COMPANY, INCORPORATED (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |
| EP-0156433-A2 | Anti-virally active pyridazinamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1985-10-02 | — | — | EP | disclosed |
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318689-A1 | Processes To Make Apoptosis Promoters | BAX, BCL2, CCAR2 | HPGD 2451/4885HTT 3001/4885ALDH1A1 3738/4885 |
| US-20100022773-A1 | APOPTOSIS PROMOTERS | BAX, BCL2, API5 | HPGD 1399/4885HTT 3472/4885ALDH1A1 3731/4885 |
| US-20260092057-A1 | BCL-XL/BCL-2 DEGRADERS AND USES THEREOF | BCL2L2, BCL2A1, BCL2L1 | HPGD 1899/4885HTT 2916/4885ALDH1A1 1304/4885 |
| US-20260001893-A1 | SMALL MOLECULE MODULATORS OF STAT6 | STAT6, NCOR1, NCOR2 | HPGD 3666/4885HTT 3252/4885ALDH1A1 3636/4885 |
| US-20260014147-A1 | STAT6 DEGRADERS | STAT6, NCOR1, CBR1 | HPGD 1725/4885HTT 1870/4885ALDH1A1 1790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.