Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.54 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.52 |
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283845 | 0.94 | KCNH2 (0.53) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6284361 | 0.89 | RXFP1 (0.57) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6286356 | 0.89 | RXFP1 (0.59) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6283194 | 0.84 | KCNH2 (0.55) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6280370 | 0.84 | RXFP1 (0.63) | RXFP1KCNH2POLA1ALDH1A1 | |
| SCHEMBL6288991 | 0.84 | MLLT1 (0.55) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6285883 | 0.83 | RXFP1 (0.62) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6286644 | 0.81 | KCNH2 (0.52) | RXFP1KCNH2MLLT1POLA1ALDH1A1 | |
| SCHEMBL6286363 | 0.80 | CLK1 (0.49) | RXFP1ALDH1A1NPC1RAB9A | |
| SCHEMBL6287491 | 0.79 | CLK1 (0.47) | RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176366-A1 | Method of preventing or treating atherosclerosis or restenosis | WATHEN MICHAEL W | 2004-09-09 | — | — | US | claimed |
| US-20040142928-A1 | Heterocycle carboxamides as antiviral agents | BUNDY GORDON L (US) | 2004-07-22 | — | — | US | claimed |
| US-20030207880-A1 | Heterocycle carboxamides as antiviral agents | BUNDY GORDON L (US) | 2003-11-06 | — | — | US | claimed |
| US-20020025960-A1 | Heterocycle carboxamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2002-02-28 | — | — | US | claimed |
| US-6903097-B2 | Heterocycle carboxamides as antiviral agents | PHARMACIA & UPJOHN COMPANY (US) | 2005-06-07 | — | — | US | disclosed |
| US-20040176366-A1 | Method of preventing or treating atherosclerosis or restenosis | WATHEN MICHAEL W | 2004-09-09 | — | — | US | disclosed |
| US-20040142928-A1 | Heterocycle carboxamides as antiviral agents | BUNDY GORDON L (US) | 2004-07-22 | — | — | US | disclosed |
| US-20030207880-A1 | Heterocycle carboxamides as antiviral agents | BUNDY GORDON L (US) | 2003-11-06 | — | — | US | disclosed |
| US-6559145-B2 | Herpes virus | PHARMACIA & UPJOHN COMPANY | 2003-05-06 | — | — | US | disclosed |
| US-20020025960-A1 | Heterocycle carboxamides as antiviral agents | PHARMACIA & UPJOHN COMPANY | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176366-A1 | Method of preventing or treating atherosclerosis or restenosis | LDLR, NR1H3, NR1H2 | RXFP1 47/4885KCNH2 4095/4885MLLT1 3151/4885 |
| US-20040142928-A1 | Heterocycle carboxamides as antiviral agents | ZC3HAV1, ZC3HAV1L, HDAC1 | RXFP1 3897/4885KCNH2 919/4885MLLT1 2478/4885 |
| US-20020025960-A1 | Heterocycle carboxamides as antiviral agents | ZC3HAV1, ZC3HAV1L, HDAC1 | RXFP1 3897/4885KCNH2 919/4885MLLT1 2478/4885 |
| US-20030207880-A1 | Heterocycle carboxamides as antiviral agents | ZC3HAV1, ZC3HAV1L, HDAC1 | RXFP1 3897/4885KCNH2 919/4885MLLT1 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.