SCHEMBL6280302

SCHEMBL6280302

CN(Cc1nc2c(N)nc3ccccc3c2n1CCN1CCCS1(=O)=O)C(N)=O

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.45
TLR8 Q9NR97 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280324 0.92 TLR7 (0.44) TLR7TLR8
SCHEMBL5124550 0.83 TLR7 (0.54) TLR7TLR8
Hydrochloric Acid SCHEMBL6280065 0.82 TLR7 (0.53) TLR7TLR8
SCHEMBL5129337 0.82 TLR7 (0.44) TLR7TLR8
SCHEMBL6280649 0.80 TLR7 (0.53) TLR7TLR8
Acetic Acid SCHEMBL5129258 0.79 TLR7 (0.52) TLR7TLR8
SCHEMBL3911428 0.79 TLR7 (0.68) TLR7TLR8
SCHEMBL5117023 0.78 TLR7 (0.61) TLR7TLR8
Hydrochloric Acid SCHEMBL5457157 0.78 TLR7 (0.48) TLR7TLR8
SCHEMBL5807038 0.78 TLR7 (0.46) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005123079-A2 UREA SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-29 WO disclosed