SCHEMBL6280449

SCHEMBL6280449

O=[C]CSC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6692913 0.69
SCHEMBL9298481 0.69
SCHEMBL3939068 0.65
SCHEMBL11574294 0.65
SCHEMBL9702622 0.63
SCHEMBL23706616 0.62
SCHEMBL8506805 0.60
SCHEMBL20556429 0.60
SCHEMBL9298892 0.60
SCHEMBL7050718 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US claimed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US claimed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US claimed
EP-0000645-B1 ISOPENICILLINS, PROCESSES FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING THEM SMITHKLINE BECKMAN CORPORATION (US) 1981-01-28 EP claimed
US-4232151-A ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-11-04 US claimed
US-4144333-A Monocyclic beta-lactams with antibacterial activity SMITHKLINE CORPORATION (US) 1979-03-13 US claimed
EP-0000645-A1 Isopenicillins, processes for their preparation, and compositions containing them SMITHKLINE BECKMAN CORPORATION (US) 1979-02-07 EP claimed
US-4122086-A Isopenicillins SMITHKLINE CORPORATION (US) 1978-10-24 US claimed
US-20210309619-A1 ISOXAZOLIN-5-ONE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-10-07 US disclosed
US-11109593-B2 Isoxazolin-5-one derivative and herbicide containing same as active ingredient HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2021-09-07 US disclosed
EP-3828176-A1 ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT Hokko Chemical Industry Co., Ltd. (JP) 2021-06-02 EP disclosed
US-20200267985-A1 ISOXAZOLIN-5-ONE DERIVATIVE AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2020-08-27 US disclosed
WO-2020022350-A1 ISOXAZOLIN-5-ONE DERIVATIVE, AND HERBICIDE CONTAINING SAME AS ACTIVE INGREDIENT 北興化学工業株式会社 2020-01-30 WO disclosed
US-20190276641-A1 RESIN COMPOSITION AND RESIN MOLDED BODY FUJI XEROX CO., LTD. (JP) 2019-09-12 US disclosed
US-4103086-A 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives SMITHKLINE CORPORATION (US) 1978-07-25 US disclosed
US-4101657-A Cephamycins as antibacterial agents SMITHKLINE CORPORATION (US) 1978-07-18 US disclosed
US-4089956-A 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof SMITHKLINE CORPORATION (US) 1978-05-16 US disclosed
US-4072674-A FOR CEPHALOSPORIN CONGENERS SMITHKLINE CORPORATION (US) 1978-02-07 US disclosed
US-4059578-A ANTIBACTERIAL SMITHKLINE CORPORATION (US) 1977-11-22 US disclosed
US-4028355-A Cephalosporin purification process SMITHKLINE CORPORATION (US) 1977-06-07 US disclosed