Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 8/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3150860 | 1.00 | KDR (0.53) | KDRCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL448621 | 0.91 | KDR (0.66) | KDRFLT1 | |
| SCHEMBL197790 | 0.91 | KDR (0.66) | KDRFLT1 | |
| SCHEMBL1577805 | 0.91 | KDR (0.66) | KDRFLT1 | |
| SCHEMBL3154554 | 0.88 | KDR (0.47) | KDRCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3155284 | 0.88 | KDR (0.47) | KDRCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL3150841 | 0.88 | KDR (0.47) | KDRCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL13417761 | 0.88 | KDR (0.47) | KDRCHRNB1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6103548 | 0.88 | KDR (0.57) | KDRFLT1MEN1ALDH1A1LMNA | |
| SCHEMBL201280 | 0.88 | KDR (0.57) | KDRFLT1MEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537084-A1 | SUBSTITUTED 2-ALKYLAMINE NICOTINIC AMIDE DERIVATIVES AND USE THERE OF | Amgen Inc. (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004007458-A1 | SUBSTITUTED 2-ALKYLAMINE NICOTINIC AMIDE DERIVATIVES AND USE THERE OF | AMGEN INC. (US) | 2004-01-22 | — | — | WO | disclosed |