Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.78 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.78 |
| ▸ | LCK | P06239 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251815 | 0.89 | KDR (0.82) | KDRFGFR1LCK | |
| SCHEMBL5251696 | 0.88 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5246405 | 0.87 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5247450 | 0.87 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5253006 | 0.85 | KDR (0.82) | KDRFGFR1LCK | |
| SCHEMBL5255796 | 0.84 | KDR (0.87) | KDRFGFR1LCK | |
| SCHEMBL5254064 | 0.84 | KDR (0.81) | KDRFGFR1LCK | |
| SCHEMBL5250940 | 0.83 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5254038 | 0.83 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5252906 | 0.81 | KDR (1.00) | KDRFGFR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891044-B2 | Indazole compounds and pharmaceutical compositions for Inhibiting protein kinases, and methods for their use | AGOURON PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |