Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.86 |
| ▸ | FGFR1 | P11362 | 10/20 | 0.77 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251964 | 1.00 | KDR (0.86) | KDRFGFR1LCK | |
| SCHEMBL5249587 | 0.93 | KDR (1.00) | KDRFGFR1LCK | |
| SCHEMBL5249039 | 0.90 | KDR (0.75) | KDRFGFR1LCK | |
| SCHEMBL5252485 | 0.87 | FGFR1 (1.00) | KDRFGFR1LCK | |
| SCHEMBL5254244 | 0.87 | KDR (1.00) | KDRFGFR1LCK | |
| Hydrochloric Acid SCHEMBL5249813 | 0.86 | KDR (0.98) | KDRFGFR1LCK | |
| SCHEMBL5252059 | 0.85 | FGFR1 (1.00) | KDRFGFR1LCK | |
| SCHEMBL5252080 | 0.83 | KDR (1.00) | KDRFGFR1 | |
| SCHEMBL5251047 | 0.83 | FGFR1 (0.83) | KDRFGFR1LCK | |
| Hydrochloric Acid SCHEMBL5248992 | 0.83 | KDR (0.99) | KDRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6891044-B2 | Indazole compounds and pharmaceutical compositions for Inhibiting protein kinases, and methods for their use | AGOURON PHARMACEUTICALS, INC. (US) | 2005-05-10 | — | — | US | disclosed |