Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281134 | 1.00 | CFTR (0.66) | CFTR | |
| Trifluoroacetic Acid SCHEMBL6504268 | 0.95 | CFTR (0.60) | CFTR | |
| Trifluoroacetic Acid SCHEMBL6275014 | 0.95 | CFTR (0.60) | CFTR | |
| Trifluoroacetic Acid SCHEMBL6504278 | 0.91 | CFTR (0.57) | CFTR | |
| Trifluoroacetic Acid SCHEMBL6504281 | 0.91 | CFTR (0.57) | CFTR | |
| SCHEMBL6493420 | 0.85 | CFTR (0.77) | CFTR | |
| SCHEMBL6278783 | 0.84 | CFTR (0.70) | CFTR | |
| SCHEMBL6279364 | 0.84 | CFTR (0.69) | CFTR | |
| SCHEMBL6279000 | 0.83 | CFTR (0.89) | CFTR | |
| Trifluoroacetic Acid SCHEMBL6494099 | 0.83 | CFTR (0.60) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005048916-A2 | TETRAHYDROSPIRO-BETA-CARBOLINE-1,3 '-PYRROLIDINE DERIVATIVES AND THEIR USE IN GHSR-RELATED DISORDERS | BIOVITRUM AB (SE) | 2005-06-02 | — | — | WO | claimed |