Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128275 | 1.00 | PTGDR2 (0.80) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4128278 | 1.00 | PTGDR2 (0.80) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4123105 | 0.89 | PTGDR2 (1.00) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4129471 | 0.89 | PTGDR2 (1.00) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4130194 | 0.89 | PTGDR2 (1.00) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4114648 | 0.89 | PTGDR2 (1.00) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4123776 | 0.86 | PTGDR2 (0.78) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4123780 | 0.86 | PTGDR2 (0.78) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4117050 | 0.83 | PTGDR2 (0.73) | PTGDR2MEN1KMT2ALMNAHTT | |
| SCHEMBL4117047 | 0.83 | PTGDR2 (0.73) | PTGDR2MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556047-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004032848-A2 | PGD2 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2004-04-22 | — | — | WO | disclosed |