SCHEMBL6281449

SCHEMBL6281449

COC(=O)CC(C(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
HSD17B10 Q99714 2/20 0.43
MGAM O43451 1/20 0.43
GAA P10253 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SLC1A1 P43005 1/20 0.39
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TET2 Q6N021 1/20 0.36
TGFBR1 P36897 1/20 0.35
KCNA5 P22460 1/20 0.35
RECQL P46063 2/20 0.34
CA12 O43570 1/20 0.34
CA14 Q9ULX7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28850755 0.87 MGAM (0.44) TSHRHSD17B10MGAMGAASI
SCHEMBL3413685 0.84 MGAM (0.41) TSHRHSD17B10MGAMGAASI
SCHEMBL25035664 0.82 MGAM (0.39) TSHRHSD17B10MGAMGAASI
SCHEMBL6043806 0.81 TDP1 (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL9125907 0.81 MGAM (0.48) TSHRHSD17B10MGAMGAASI
SCHEMBL8669433 0.81 SLC1A1 (0.47) TSHRHSD17B10MGAMGAASI
SCHEMBL6442162 0.81 TSHR (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL6516076 0.80 TSHR (0.36) TSHRHSD17B10MGAMGAASI
SCHEMBL1623432 0.79 SMN1; SMN2 (0.52) TSHRHSD17B10MGAMGAASI
SCHEMBL12156901 0.79 SMN1; SMN2 (0.52) TSHRHSD17B10MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665253-A1 Coatings based on fluoropolyethers AUSIMONT S.p.A. (IT) 1995-08-02 EP claimed
US-6864287-B1 Derivatives of dicarboxylic acid having pharmaceutical properties BAYER AKTIENGESELLSCHAFT (DE) 2005-03-08 US disclosed
US-6350306-B1 PAINTS AND COATINGS, ?HIGH DRY?COMPOSITIONS BASED ON FLUORINE CONTAINING POLYMERS AUSIMONT S.P.A. (IT) 2002-02-26 US disclosed
EP-0665253-B1 Coatings based on fluoropolyethers AUSIMONT SPA (IT) 2001-08-16 EP disclosed
EP-0731125-B1 Coatings based on fluoropolyethers AUSIMONT SPA (IT) 2001-07-04 EP disclosed
US-5959058-A Coatings based on fluoropolyethers AUSIMONT S.P.A. (IT) 1999-09-28 US disclosed
EP-0731125-A1 Coatings based on fluoropolyethers AUSIMONT S.p.A. (IT) 1996-09-11 EP disclosed
EP-0665253-A1 Coatings based on fluoropolyethers AUSIMONT S.p.A. (IT) 1995-08-02 EP disclosed