Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.43 |
| ▸ | F2 | P00734 | 9/20 | 0.43 |
| ▸ | PLG | P00747 | 5/20 | 0.43 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6281652 | 0.82 | F10 (0.62) | F10PRSS1F2PLGPROC | |
| SCHEMBL7410111 | 0.80 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7515067 | 0.80 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL7411495 | 0.80 | F10 (0.69) | F10PRSS1F2PLGPROC | |
| SCHEMBL6275985 | 0.79 | F10 (0.42) | F10PRSS1F2PLGPROC | |
| SCHEMBL7408558 | 0.79 | F10 (0.48) | F10PRSS1F2PLGPROC | |
| SCHEMBL7408430 | 0.79 | F10 (0.48) | F10PRSS1F2PLGPROC | |
| SCHEMBL7408226 | 0.79 | F10 (0.47) | F10PRSS1F2PLGPROC | |
| SCHEMBL7415455 | 0.78 | F10 (0.57) | F10PRSS1F2PLGPROC | |
| SCHEMBL7417409 | 0.78 | F10 (0.57) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | claimed |