⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6284355 | 1.00 | — | — | |
| SCHEMBL5546804 | 0.81 | — | — | |
| SCHEMBL31376763 | 0.81 | — | — | |
| SCHEMBL6286662 | 0.81 | — | — | |
| SCHEMBL1472688 | 0.81 | — | — | |
| SCHEMBL25316458 | 0.81 | — | — | |
| SCHEMBL9413595 | 0.71 | — | — | |
| SCHEMBL9812132 | 0.69 | — | — | |
| SCHEMBL25891770 | 0.68 | — | — | |
| SCHEMBL26756668 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960573-B2 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED (JP) | 2005-11-01 | — | — | US | disclosed |
| US-6867313-B2 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED (JP) | 2005-03-15 | — | — | US | disclosed |
| US-6689766-B2 | ALSO FOR TREATING MALIGNANT TUMORS, RHEUMATOID ARTHRITIS, OSTEOPOROSIS, DIABETES MELLITUS, HYPERTENSION, ALOPECIA, ACNE, PSORIASIS, DERMATITIS, HYPERCALCEMIA, HYPOPARATHYROIDISM AND METABOLIC DISORDER OF CARTILAGE. | TEIJIN LIMITED (JP) | 2004-02-10 | — | — | US | disclosed |
| US-6548489-B2 | Also for treating malignant tumors, rheumatoid arthritis, osteoporosis, diabetes mellitus, hypertension, alopecia, acne, psoriasis, dermatitis, hypercalcemia, hypoparathyroidism and metabolic disorder of cartilage. | TEIJIN LIMITED (JP) | 2003-04-15 | — | — | US | disclosed |
| US-6531460-B1 | Vitamin D3 derivatives | TEIJIN LIMITED (JP) | 2003-03-11 | — | — | US | disclosed |
| US-20020132799-A1 | Vitamin D3 dervative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-09-19 | — | — | US | disclosed |
| US-20020103173-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-08-01 | — | — | US | disclosed |
| US-20020099039-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-07-25 | — | — | US | disclosed |
| US-20020091109-A1 | Vitamin D3 derivative and treating agent for inflammatory respiratory disease using same | TEIJIN LIMITED | 2002-07-11 | — | — | US | disclosed |
| EP-0854139-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-1123921-A1 | VITAMIN D 3? DERIVATIVES AND REMEDIES FOR INFLAMMATORY RESPIRATORY DISEASES CONTAINING THE SAME | TEIJIN LIMITED (JP) | 2001-08-16 | — | — | EP | disclosed |
| EP-0854138-B1 | Vitamin D3 derivative and production process thereof | TEIJIN LTD (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-6177586-B1 | USEFUL AS A PHARMACEUTICAL SUCH AS AN AGENT FOR PROMOTING BONE FORMATION, AN AGENT FOR SUPPRESSING PROLIFERATION OF TUMOR CELLS, AN AGENT FOR HIGH CALCIUM BLOOD DISEASES, AND AN IMMUNOSUPPRESSION AGENT | TEIJIN LIMITED (JP) | 2001-01-23 | — | — | US | disclosed |
| EP-0712843-B1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5986112-A | STEROID DERIVATIVES AS ANTITUMOR AGENTS AND BLOOD METAL CONCENTRATES | TEIJIN LIMITED (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0854138-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| EP-0854139-A2 | Vitamin D3 derivative and production process thereof | TEIJIN LIMITED (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5719297-A | Vitamin D3 derivatives and production process thereof | TEIJIN LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0712843-A1 | VITAMIN D3 DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TEIJIN LIMITED (JP) | 1996-05-22 | — | — | EP | disclosed |