Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ASPH | Q12797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8856874 | 0.69 | CES1 (0.39) | CES1MAPK1HTTIDO1KDM4E | |
| SCHEMBL2068758 | 0.68 | CHIA (0.38) | HTTL3MBTL1KDM4EALDH1A1KMT2A | |
| SCHEMBL2068190 | 0.67 | GLA (0.34) | KDM4EALDH1A1KMT2A | |
| SCHEMBL2069207 | 0.66 | SMN1; SMN2 (0.50) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL31146203 | 0.66 | KDM4E (0.47) | CES1MAPK1HTTL3MBTL1KDM4E | |
| SCHEMBL26917325 | 0.66 | NAPRT (0.61) | CES1MAPK1ATML3MBTL1KDM4E | |
| SCHEMBL1921049 | 0.64 | CES1 (0.34) | CES1MAPK1HTTIDO1PLA2G2D | |
| Hydrochloric Acid SCHEMBL27227698 | 0.64 | NAPRT (0.59) | CES1MAPK1ATML3MBTL1KDM4E | |
| SCHEMBL15414819 | 0.64 | SIRT3 (0.36) | MAPK1HTTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3037744 | 0.63 | MAPT (0.50) | CES1MAPK1HTTIDO1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927193-B2 | Aryl ether derivatives and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2005-08-09 | — | — | US | disclosed |
| US-6613718-B2 | 2,3-Dihydro-2-thioxo-pyrimidinone derivatives | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-6479435-B1 | OR DIARYL SULFIDES, 1-(4-CHLORO-2-FLUORO-5-(2-PYRIMIDYLOXY)PHENYL)-4-DIFLUOROMETHY L-3-METHYL-1,4-DIHYDRO-1,2,4-TRIAZOLIN-5-ONE FOR EXAMPLE | ISK AMERICAS INCORPORATED | 2002-11-12 | — | — | US | disclosed |
| US-6333296-B1 | FOR CONTRILLING WEEDS | ISK AMERICAS INCORPORATED | 2001-12-25 | — | — | US | disclosed |
| US-6303543-B1 | Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-10-16 | — | — | US | disclosed |
| US-6121201-A | HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |