Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | PLG | P00747 | 4/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | PROC | P04070 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275428 | 0.89 | F10 (0.51) | F10PRSS1F2PLGPROC | |
| SCHEMBL6282114 | 0.87 | F10 (0.48) | F10PRSS1F2PLGPROC | |
| SCHEMBL6278912 | 0.85 | F10 (0.47) | F10PRSS1F2PLGROCK1 | |
| SCHEMBL6285035 | 0.85 | F10 (0.47) | F10PRSS1F2PLGROCK1 | |
| SCHEMBL7392277 | 0.85 | F10 (0.47) | F10PRSS1F2PLGROCK1 | |
| SCHEMBL6278788 | 0.84 | F10 (0.46) | F10PRSS1F2PLGROCK1 | |
| SCHEMBL6279424 | 0.84 | F10 (0.47) | F10PRSS1F2PLGPROC | |
| SCHEMBL7381108 | 0.84 | F10 (0.49) | F10PRSS1F2PLGPROC | |
| SCHEMBL7116039 | 0.82 | F10 (0.67) | F10PRSS1F2PLGPROC | |
| SCHEMBL6280320 | 0.81 | F10 (0.51) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |