SCHEMBL6282124

SCHEMBL6282124

CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCN(CCSc2nc3cccc(C(=O)/C=C/N(C)C)c3o2)CC1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 13/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282129 1.00 SOAT1 (0.67) SOAT1
SCHEMBL6284794 0.88 SOAT1 (0.75) SOAT1
SCHEMBL6279638 0.86 SOAT1 (0.73) SOAT1
SCHEMBL6214292 0.84 SOAT1 (0.72) SOAT1
SCHEMBL6214295 0.84 SOAT1 (0.72) SOAT1
SCHEMBL6282647 0.83 SOAT1 (0.77) SOAT1
SCHEMBL6284053 0.83 SOAT1 (0.75) SOAT1
SCHEMBL6282995 0.82 SOAT1 (0.74) SOAT1
SCHEMBL6280351 0.82 SOAT1 (0.74) SOAT1
SCHEMBL6282203 0.81 SOAT1 (0.73) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969711-B2 Cyclic diamine compounds and medicine containing the same KOWA COMPANY, LTD. (JP) 2005-11-29 US disclosed
EP-0987254-B1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME KOWA CO (JP) 2004-12-22 EP disclosed
EP-0987254-A1 NOVEL CYCLIC DIAMINE COMPOUNDS AND MEDICINE CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-03-22 EP disclosed