Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 9/20 | 0.77 |
| ▸ | EP300 | Q09472 | 1/20 | 0.66 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.66 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.57 |
| ▸ | EIF4E | P06730 | 1/20 | 0.57 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905845 | 1.00 | MAP3K5 (0.77) | MAP3K5EP300CREBBPENPP2MEN1 | |
| SCHEMBL3905850 | 1.00 | MAP3K5 (0.77) | MAP3K5EP300CREBBPENPP2MEN1 | |
| SCHEMBL3897828 | 0.91 | MAP3K5 (0.78) | MAP3K5ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL3897831 | 0.91 | MAP3K5 (0.78) | MAP3K5ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL3963776 | 0.91 | MAP3K5 (0.64) | MAP3K5EP300CREBBPENPP2MEN1 | |
| SCHEMBL3963779 | 0.91 | MAP3K5 (0.64) | MAP3K5EP300CREBBPENPP2MEN1 | |
| SCHEMBL13762522 | 0.90 | MAP3K5 (0.62) | MAP3K5EP300CREBBPENPP2MEN1 | |
| SCHEMBL3900350 | 0.89 | MAP3K5 (0.78) | MAP3K5ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL3900346 | 0.89 | MAP3K5 (0.78) | MAP3K5ENPP2MEN1KMT2AALDH1A1 | |
| SCHEMBL3903171 | 0.87 | MAP3K5 (0.70) | MAP3K5EP300CREBBPENPP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |