Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22548038 | 0.73 | CDK5 (0.37) | KMT2A | |
| SCHEMBL12501529 | 0.72 | — | — | |
| SCHEMBL8893 | 0.70 | ABCB1 (0.36) | — | |
| SCHEMBL20096241 | 0.68 | — | — | |
| SCHEMBL20096233 | 0.68 | — | — | |
| SCHEMBL16358128 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL25233458 | 0.67 | — | — | |
| Hydrogen Peroxide SCHEMBL9193981 | 0.67 | ABCB1 (0.34) | KMT2A | |
| Hydrochloric Acid SCHEMBL31645494 | 0.67 | — | — | |
| SCHEMBL16338940 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916838-B1 | 1-benzylpyrazole-3-carboxylic acid tricyclic derivatives as cannabinoid receptor antagonists | SANOFI-AVENTIS (FR) | 2005-07-12 | — | — | US | disclosed |
| EP-1230222-B1 | 1-BENZYLPYRAZOLES-3-CARBOXYLIC ACID TRICYCLIC DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2004-07-07 | — | — | EP | disclosed |
| EP-1230222-A1 | 1-BENZYLPYRAZOLES-3-CARBOXYLIC ACID TRICYCLIC DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032629-A1 | 1-BENZYLPYRAZOLES-3-CARBOXYLIC ACID TRICYCLIC DERIVATIVES AS CANNABINOID RECEPTOR ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 2001-05-10 | — | — | WO | disclosed |