SCHEMBL6282585

SCHEMBL6282585

CNC(=O)NCc1nc2c(N)nc3cccnc3c2n1CCCCNC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.44
TLR8 Q9NR97 12/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5120459 0.91 TLR7 (0.47) TLR7TLR8
SCHEMBL5129487 0.88 TLR7 (0.46) TLR7TLR8
SCHEMBL6759213 0.85 TLR7 (0.56) TLR7TLR8
SCHEMBL5129325 0.80 TLR7 (0.53) TLR7TLR8
SCHEMBL8142637 0.80 TLR7 (0.54) TLR7TLR8
SCHEMBL3358614 0.80 TLR7 (0.57) TLR7TLR8
SCHEMBL3355143 0.80 TLR7 (0.54) TLR7TLR8
SCHEMBL1490794 0.79 TLR7 (0.41) TLR7TLR8
SCHEMBL22359230 0.78 TLR7 (0.48) TLR7TLR8
Acetic Acid SCHEMBL5128218 0.78 TLR7 (0.52) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005123079-A2 UREA SUBSTITUTED IMIDAZOPYRIDINES, IMIDAZOQUINOLINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-29 WO disclosed