Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.60 |
| ▸ | LTA4H | P09960 | 4/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6279523 | 1.00 | NR5A1 (0.60) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6283222 | 1.00 | NR5A1 (0.60) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6285365 | 0.87 | NR5A1 (0.49) | NR5A1LTA4HPTPN1KDM4EALDH1A1 | |
| SCHEMBL6285972 | 0.86 | PTPN1 (0.56) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6282177 | 0.86 | PTPN1 (0.56) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6279323 | 0.86 | PTPN1 (0.56) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6279663 | 0.86 | PTPN1 (0.56) | NR5A1LTA4HPTPN1RARBKDM4E | |
| SCHEMBL6288297 | 0.85 | PTPN1 (0.57) | NR5A1PTPN1KDM4EALDH1A1MAPT | |
| SCHEMBL6279204 | 0.83 | PTPN1 (0.56) | PTPN1KDM4EALDH1A1MAPTCYP1A2 | |
| SCHEMBL6287275 | 0.82 | PTPN1 (0.59) | PTPN1RARBKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | NR5A1 160/4885LTA4H 4503/4885PTPN1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.