Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.72 |
| ▸ | PTPRC | P08575 | 2/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3907098 | 0.83 | PTPN1 (1.00) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3905734 | 0.81 | PTPN1 (0.81) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3904925 | 0.76 | PTPN1 (0.60) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3905887 | 0.74 | PTPN1 (0.79) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3908129 | 0.74 | PTPN1 (0.79) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3909628 | 0.74 | PTPN1 (0.69) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907455 | 0.73 | PTPN1 (0.67) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907607 | 0.73 | PTPN1 (1.00) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907720 | 0.72 | PTPN1 (0.63) | PTPN1PTPRCPTPN2 | |
| SCHEMBL3907037 | 0.72 | PTPN1 (0.64) | PTPN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081954-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |