Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.69 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362064 | 0.91 | CYP4F2 (0.65) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL18455674 | 0.89 | CYP4F2 (0.71) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL9357799 | 0.88 | CYP4F2 (0.62) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL9381508 | 0.88 | CYP4F2 (0.61) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL28581664 | 0.87 | CYP4F2 (0.61) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL26683190 | 0.86 | CYP4F2 (0.56) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL6759893 | 0.86 | CYP4F2 (0.52) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL18458202 | 0.86 | CYP4F2 (0.67) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL10566622 | 0.85 | CYP4F2 (0.50) | CYP4F2CYP4A11PTPN1ALDH1A1GAA | |
| SCHEMBL69660 | 0.85 | CYP4F2 (0.86) | CYP4F2CYP4A11PTPN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114887666-A | Catalyst and application thereof | 山东师范大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-112778115-B | Preparation method of flurbiprofen | 山东师范大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-112778115-A | Preparation method of flurbiprofen | 山东师范大学 | 2021-05-11 | — | — | CN | disclosed |
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| CN-1589261-A | Piperidine derivatives and their use as modulators of chemokine receptor activity (especially CCR5) | ASTRAZENECA AB (SE) | 2005-03-02 | — | — | CN | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0470832-B1 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI CHEMICAL IND (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5136090-A | Antidiabetic agents | TOYO JOZO KABUSHIKI KAISHA (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0470832-A2 | Biphenyl 5,5'-bis-alkanoic acid derivatives, their production and use thereof | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1992-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | CYP4F2 1593/4885CYP4A11 1052/4885PTPN1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.