⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736985 | 0.79 | — | — | |
| SCHEMBL2161855 | 0.67 | — | — | |
| SCHEMBL10681570 | 0.67 | CYP2E1 (0.36) | — | |
| SCHEMBL954216 | 0.67 | — | — | |
| SCHEMBL14038643 | 0.66 | — | — | |
| SCHEMBL28181955 | 0.66 | — | — | |
| SCHEMBL5026008 | 0.65 | SMN1; SMN2 (0.60) | — | |
| Hydrochloric Acid SCHEMBL28442510 | 0.65 | — | — | |
| SCHEMBL16793195 | 0.64 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL10431196 | 0.64 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802615-A1 | PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceuticals Corporation (US) | 2007-07-04 | — | — | EP | claimed |
| WO-2006044955-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | claimed |
| CN-102718731-B | 4 /5-methyl-1, 2, 3-thiadiazole formic acid derivative and preparation method thereof | TIANJIN UNIVERSITY OF COMMERCE (CN) | 2014-10-01 | — | — | CN | disclosed |
| CN-102718731-A | 4 /5-methyl-1, 2, 3-thiadiazole formic acid derivative and preparation method thereof | UNIV TIANJIN COMMERCE | 2012-10-10 | — | — | CN | disclosed |
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |
| CN-1163139-C | Agricultural and horticultural disease controller and method for controlling diseases | �ձ��ݶ�ũҩ��ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| CN-1180297-A | Agricultural and horticultural disease control agent and method for controlling these diseases | NIHON NOHYAKU CO LTD (JP) | 1998-04-29 | — | — | CN | disclosed |