⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263435 | 0.78 | — | — | |
| SCHEMBL5532955 | 0.75 | — | — | |
| SCHEMBL9868078 | 0.75 | — | — | |
| SCHEMBL9587651 | 0.75 | — | — | |
| SCHEMBL6595865 | 0.75 | — | — | |
| SCHEMBL14319121 | 0.73 | — | — | |
| SCHEMBL539017 | 0.73 | — | — | |
| Amylene Hydrate SCHEMBL756239 | 0.73 | — | — | |
| SCHEMBL27407206 | 0.73 | — | — | |
| SCHEMBL5460994 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023207949-A1 | FUSED RING COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2023-11-02 | — | — | WO | claimed |
| CN-116947713-A | Ring-merging compound and application thereof | 中国科学院上海药物研究所 | 2023-10-27 | — | — | CN | claimed |
| EP-3191478-A1 | COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS | Novartis AG (CH) | 2017-07-19 | — | — | EP | claimed |
| US-9487494-B2 | Cyclic hydrocarbon compounds for the treatment of diseases | LEO PHARMA A/S (DK) | 2016-11-08 | — | — | US | claimed |
| WO-2016038582-A1 | COMPOUNDS AND COMPOSITIONS AS RAF KINASE INHIBITORS | NOVARTIS AG (CH) | 2016-03-17 | — | — | WO | claimed |
| US-20100317582-A1 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-12-16 | — | — | US | claimed |
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | claimed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | claimed |
| EP-1636219-B1 | NOVEL THIAZOLYLMETHYL PYRAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN DYES FOR KERATIN FIBERS | WELLA AG (DE) | 2006-11-02 | — | — | EP | claimed |
| US-20060183781-A1 | Novel thiazolylmethyl pyrazoles, method for the production thereof, and use thereof in dyes for keratin fibers | WELLA AG (DE) | 2006-08-17 | — | — | US | claimed |
| EP-0809626-B1 | PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED ALPHA, ALPHA DIAROMATIC METHANOLS | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| EP-0809626-A1 | PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED $g(a),$g(a)-DIAROMATIC METHANOLS | Novartis AG (CH) | 1997-12-03 | — | — | EP | claimed |
| US-5646330-A | REDUCING AN ASYMMETRIC BIAROMATIC KETONE WITH AN ISOPINOCAMPHENYLBORANE REDUCING AGENT | CIBA-GEIGY CORPORATION (US) | 1997-07-08 | — | — | US | claimed |
| WO-1996025390-A1 | PRODUCTION OF ENANTIOMERICALLY ENRICHED ORTHO-SUBSTITUTED α,α-DIAROMATIC METHANOLS | NOVARTIS AG (CH) | 1996-08-22 | — | — | WO | claimed |
| EP-0292761-B1 | Pyridoxamine chelating compounds, manganese (II) chelates and their use as NMRI contrast agents | NYCOMED SALUTAR INC (US) | 1994-02-02 | — | — | EP | claimed |
| EP-0185079-B1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1988-10-19 | — | — | EP | claimed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | claimed |
| EP-0078158-B1 | NOVEL ALKANE AND ALKENE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1986-09-10 | — | — | EP | claimed |
| EP-0185079-A1 | — | CIBA GEIGY AG | 1986-06-25 | — | — | EP | claimed |
| WO-1986000066-A1 | N-SUBSTITUTED BUTYRAMIDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1986-01-03 | — | — | WO | claimed |