SCHEMBL6283707

SCHEMBL6283707

CC(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccc2ccccc2c1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNJ11 Q14654 11/20 0.37
ABCC9 O60706 6/20 0.37
ABCC8 Q09428 6/20 0.37
KCNJ8 Q15842 6/20 0.37
CYP2D6 P10635 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC2A1 P11166 1/20 0.36
CTRB1 P17538 1/20 0.35
MPL P40238 1/20 0.34
CTRC Q99895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6282879 0.85 NR1I2 (0.46) KCNJ11ABCC9ABCC8KCNJ8KDM4E
SCHEMBL6283746 0.85 CYP2D6 (0.42) CYP2D6ALDH1A1HPGDHSD17B10CTRB1
SCHEMBL6281667 0.83 CYP2D6 (0.40) CYP2D6ALDH1A1HPGDHSD17B10CTRB1
SCHEMBL3495406 0.81 NR1I2 (0.44) KCNJ11ABCC9ABCC8KCNJ8CYP2D6
SCHEMBL11418053 0.79 NR1I2 (0.43) KCNJ11ABCC9ABCC8KCNJ8CYP2D6
SCHEMBL11294379 0.72 CYP2D6 (0.40) KCNJ11CYP2D6HPGDKMT2AHSD17B10
SCHEMBL41541 0.71 CYP2D6 (0.53) CYP2D6ALDH1A1HSD17B10CTRB1MPL
SCHEMBL3233245 0.70 CYP2D6 (0.51) CYP2D6ALDH1A1HSD17B10CTRB1MPL
Water SCHEMBL669870 0.70 CYP2D6 (0.51) CYP2D6ALDH1A1HSD17B10CTRB1MPL
SCHEMBL4578484 0.70 CYP2D6 (0.51) CYP2D6ALDH1A1GAAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6912118-B2 Solid electrolytic capacitor SANYO ELECTRIC CO., LTD. (JP) 2005-06-28 US disclosed
US-20050088804-A1 SOLID ELECTROLYTIC CAPACITOR SANYO ELECTRIC CO., LTD. (JP) 2005-04-28 US disclosed