SCHEMBL6284231

SCHEMBL6284231

CCNCCOCCN1CCNC1=O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.35
MDM2 Q00987 1/20 0.35
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
ADORA1 P30542 1/20 0.34
MEN1 O00255 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SCN9A Q15858 5/20 0.33
POLB P06746 2/20 0.33
CREBBP Q92793 1/20 0.33
HPGDS O60760 1/20 0.33
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289602 0.98 KMT2A (0.39) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6284167 0.87 KMT2A (0.39) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6285672 0.86 TSHR (0.40) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6283934 0.85 KMT2A (0.39) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6287161 0.84 KMT2A (0.42) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6284635 0.84 KMT2A (0.49) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6290106 0.83 KMT2A (0.41) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6285538 0.81 KMT2A (0.43) KMT2ARAB9AALDH1A1KDM4ELMNA
SCHEMBL6254128 0.80 KMT2A (0.39) KMT2ARAB9AALDH1A1KDM4ETP53
SCHEMBL6287265 0.80 KMT2A (0.43) KMT2ARAB9AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed