Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.69 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.69 |
| ▸ | PLG | P00747 | 4/20 | 0.69 |
| ▸ | F2 | P00734 | 6/20 | 0.50 |
| ▸ | PROC | P04070 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395980 | 1.00 | F10 (0.69) | F10PRSS1PLGF2PROC | |
| SCHEMBL6280041 | 0.89 | F10 (0.54) | F10PRSS1PLGF2PROC | |
| SCHEMBL6278839 | 0.87 | F10 (0.54) | F10PRSS1PLGF2PROC | |
| SCHEMBL6280507 | 0.85 | F10 (0.59) | F10PRSS1PLGF2PROC | |
| SCHEMBL6281674 | 0.85 | F10 (0.61) | F10PRSS1PLGF2PROC | |
| SCHEMBL6275852 | 0.85 | F10 (0.52) | F10PRSS1PLGF2PROC | |
| SCHEMBL6279341 | 0.85 | F10 (0.52) | F10PRSS1PLGF2PROC | |
| SCHEMBL6283268 | 0.85 | F10 (0.70) | F10PRSS1PLGF2PROC | |
| SCHEMBL6281579 | 0.85 | F10 (0.70) | F10PRSS1PLGF2PROC | |
| SCHEMBL6275831 | 0.84 | F10 (0.52) | F10PRSS1PLGF2PROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6855726-B1 | Quinolones as serine protease inhibitors | WARNER-LAMBERT COMPANY LLC (US) | 2005-02-15 | — | — | US | disclosed |