SCHEMBL6285455

SCHEMBL6285455

CNCC(C)(C)CNC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2413071 0.91 SMN1; SMN2 (0.45) SMN1; SMN2HSD17B10TSHRTDP1LMNA
SCHEMBL6289593 0.82 TDP1 (0.32) TDP1
SCHEMBL24340639 0.82 SMN1; SMN2 (0.35) SMN1; SMN2HSD17B10TSHRTDP1LMNA
SCHEMBL74035 0.80
SCHEMBL21452807 0.79 SMN1; SMN2 (0.41) SMN1; SMN2HSD17B10TSHRLMNATP53
SCHEMBL9768528 0.79 SMN1; SMN2 (0.36) SMN1; SMN2HSD17B10TSHRTDP1
SCHEMBL6289599 0.79 TDP1 (0.33) TDP1
SCHEMBL6290116 0.79 SMN1; SMN2 (0.36) SMN1; SMN2HSD17B10TSHRTDP1
SCHEMBL6289594 0.78 SMN1; SMN2 (0.37) SMN1; SMN2HSD17B10TSHRTDP1LMNA
SCHEMBL18467133 0.77 SMN1; SMN2 (0.39) SMN1; SMN2HSD17B10TSHRLMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed