SCHEMBL6285599

SCHEMBL6285599

CC(C(=O)O)(c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.44
MAPT P10636 1/20 0.44
MEN1 O00255 3/20 0.43
CYP2C19 P33261 2/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HIF1A Q16665 1/20 0.42
CYP1A2 P05177 2/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674052 1.00 KMT2A (0.44) KMT2AMAPTMEN1CYP2C19CYP3A4
SCHEMBL4799382 0.79 KMT2A (0.40) KMT2AMAPTMEN1CYP2C19CYP3A4
SCHEMBL2089572 0.79 CYP1A2 (0.50) KMT2AMAPTCYP2C19CYP3A4HIF1A
SCHEMBL2089573 0.79 CYP1A2 (0.50) KMT2AMAPTCYP2C19CYP3A4HIF1A
SCHEMBL754265 0.79 CYP1A2 (0.50) KMT2AMAPTCYP2C19CYP3A4HIF1A
SCHEMBL4894696 0.78 KCNN4 (0.42) KMT2AMAPTMEN1CYP2C19CYP3A4
SCHEMBL4893317 0.78 KCNN4 (0.42) KMT2AMAPTMEN1CYP2C19CYP3A4
SCHEMBL3381201 0.78 KMT2A (0.45) KMT2AMAPTMEN1CYP2C19CYP3A4
SCHEMBL288100 0.78 MAPT (0.45) KMT2AMAPTCYP2C19CYP3A4HIF1A
SCHEMBL9437359 0.77 KMT2A (0.47) KMT2AMAPTMEN1CYP2C19CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005516365-A 2005-06-02 JP claimed
EP-1470563-A2 PHOTOVOLTAIC CELL COMPONENTS AND MATERIALS Konarka Technologies, Inc. (US) 2004-10-27 EP claimed
WO-2003065394-A2 PHOTOVOLTAIC CELL COMPONENTS AND MATERIALS KONARKA TECHNOLOGIES, INC. (US) 2003-08-07 WO claimed
CN-215608690-U Catheter equipped with extendable legs of variable length 巴德阿克塞斯系统股份有限公司 2022-01-25 CN disclosed
CN-113769244-A Catheter equipped with extendable legs of variable length 巴德阿克塞斯系统股份有限公司 2021-12-10 CN disclosed
CN-112204148-A Modified immune cells with enhanced function and screening method thereof 宾夕法尼亚大学董事会 2021-01-08 CN disclosed
EP-3413900-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS Nutrition 21, LLC (US) 2018-12-19 EP disclosed
WO-2017139337-A1 CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS NUTRITION 21, LLC (US) 2017-08-17 WO disclosed
CN-1659276-A Phospholipases, nucleic acids encoding them and methods of making and using them DIVERSA CORP (US) 2005-08-24 CN disclosed
EP-1470597-A2 PHOTOVOLTAIC FIBERS Konarka Technologies, Inc. (US) 2004-10-27 EP disclosed
EP-1470563-A2 PHOTOVOLTAIC CELL COMPONENTS AND MATERIALS Konarka Technologies, Inc. (US) 2004-10-27 EP disclosed
WO-2003065393-A2 DISPLAYS WITH INTEGRATED PHOTOVOLTAIC CELLS KONARKA TECHNOLOGIES, INC. (US) 2003-08-07 WO disclosed
WO-2003065471-A2 PHOTOVOLTAIC FIBERS KONARKA TECHNOLOGIES, INC. (US) 2003-08-07 WO disclosed
WO-2003065394-A2 PHOTOVOLTAIC CELL COMPONENTS AND MATERIALS KONARKA TECHNOLOGIES, INC. (US) 2003-08-07 WO disclosed
EP-0331404-A2 Method for producing tropane alkaloid SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) 1989-09-06 EP disclosed