Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6286719 | 0.99 | PTPN1 (0.49) | PTPN1HRH3BCHEHSD11B1LTA4H | |
| SCHEMBL6282846 | 0.96 | PTPN1 (0.48) | PTPN1HRH3BCHEHSD11B1LTA4H | |
| SCHEMBL6283361 | 0.94 | PTPN1 (0.49) | PTPN1HRH3BCHEHSD11B1LTA4H | |
| SCHEMBL6285256 | 0.94 | PTPN1 (0.49) | PTPN1HRH3BCHEHSD11B1LTA4H | |
| SCHEMBL6286409 | 0.94 | PTPN1 (0.44) | PTPN1HRH3BCHELTA4HEPHX2 | |
| SCHEMBL6278914 | 0.94 | PTPN1 (0.44) | PTPN1HRH3BCHELTA4HEPHX2 | |
| SCHEMBL6287181 | 0.94 | PTPN1 (0.44) | PTPN1HRH3BCHELTA4HEPHX2 | |
| SCHEMBL6287204 | 0.94 | PTPN1 (0.44) | PTPN1HRH3BCHELTA4HEPHX2 | |
| SCHEMBL6279173 | 0.94 | PTPN1 (0.44) | PTPN1HRH3BCHELTA4HEPHX2 | |
| SCHEMBL6278803 | 0.94 | PTPN1 (0.46) | PTPN1HRH3BCHEHSD11B1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911468-B2 | Tyrosine phosphatase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144338-A1 | Tyrosine phosphatase inhibitors | PTPRC, PTPN1, PTPRM | PTPN1 2/4885HRH3 1166/4885BCHE 4082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.