SCHEMBL6285746

SCHEMBL6285746

CCNCC(C)(C)CNC(=O)NC

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290154 0.86 SMN1; SMN2 (0.37) HSD17B10SMN1; SMN2TSHRL3MBTL1
SCHEMBL6285506 0.84 HSD17B10 (0.31) HSD17B10
SCHEMBL6287199 0.82 EPHX1 (0.40) SMN1; SMN2TSHRL3MBTL1
SCHEMBL6284472 0.82 HSD17B10 (0.32) HSD17B10
SCHEMBL6285495 0.81 HSD17B10 (0.39) HSD17B10SMN1; SMN2TSHRL3MBTL1
SCHEMBL20218457 0.81 HSD17B10 (0.35) HSD17B10SMN1; SMN2TSHRL3MBTL1
SCHEMBL20269674 0.79 SMN1; SMN2 (0.38) HSD17B10SMN1; SMN2TSHR
SCHEMBL6289695 0.78 HSD17B10 (0.30) HSD17B10
SCHEMBL6286863 0.78 EPHX1 (0.53) TSHR
SCHEMBL6289594 0.78 SMN1; SMN2 (0.37) HSD17B10SMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6916854-B2 Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints BASF AKTIENGESELLSCHAFT (DE) 2005-07-12 US disclosed
US-20040097642-A1 Unsaturated compounds containing carbamate terminal groups or urea terminal groups BASF AKTIENGESELLSCHAFT (DE) 2004-05-20 US disclosed