⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275258 | 0.67 | — | — | |
| SCHEMBL5594211 | 0.64 | — | — | |
| SCHEMBL19557111 | 0.62 | — | — | |
| SCHEMBL4757408 | 0.62 | — | — | |
| SCHEMBL8125614 | 0.61 | — | — | |
| SCHEMBL7856995 | 0.61 | — | — | |
| SCHEMBL11143077 | 0.60 | — | — | |
| SCHEMBL1861177 | 0.59 | — | — | |
| SCHEMBL3654178 | 0.59 | — | — | |
| SCHEMBL23073731 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138275-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-07-15 | — | — | US | claimed |
| US-6852761-B2 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION (US) | 2005-02-08 | — | — | US | disclosed |
| US-20040171839-A1 | Polycyclic aryl and heteroaryl substituted 1, 4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-09-02 | — | — | US | disclosed |
| US-20040171616-A9 | Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-09-02 | — | — | US | disclosed |
| US-6693121-B2 | AS INHIBITORS OF SERINE PROTEASES OF THE COAGULATION CASCADE AND COMPOUNDS, USED FOR ANTICOAGULANT THERAPY FORPROPHYLAXIS OF A VARIETY OF THROMBOTIC CONDITIONS INCLUDING CORONARY ARTERY AND CEREBROVASCULAR DISEASES | PHARMACIA CORPORATION | 2004-02-17 | — | — | US | disclosed |
| US-20030236231-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | disclosed |
| US-6660885-B2 | Serine protease inhibitor | PHARMACIA CORPORATION | 2003-12-09 | — | — | US | disclosed |
| US-20030225086-A1 | Polycyclic aryl and heteroaryl substituted 1,4-quinones useful for selective inhibition of the coagulation cascade | SOUTH MICHAEL S (US) | 2003-12-04 | — | — | US | disclosed |
| US-20020025947-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-02-28 | — | — | US | disclosed |