SCHEMBL6285785

SCHEMBL6285785

CCCCc1nc2c(N)nc3cccnc3c2n1CCCCN(Cc1ccccc1)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.57
TLR8 Q9NR97 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19435433 0.92 TLR7 (0.52) TLR7TLR8
SCHEMBL6135818 0.83 TLR7 (0.71) TLR7TLR8
SCHEMBL3355959 0.82 TLR7 (0.55) TLR7TLR8
SCHEMBL3358644 0.82 TLR7 (0.56) TLR7TLR8
SCHEMBL3358614 0.81 TLR7 (0.57) TLR7TLR8
SCHEMBL6759213 0.81 TLR7 (0.56) TLR7TLR8
SCHEMBL7142636 0.81 TLR7 (0.48) TLR7TLR8
SCHEMBL5618922 0.81 TLR7 (0.55) TLR7TLR8
SCHEMBL6757257 0.80 TLR7 (0.54) TLR7TLR8
SCHEMBL7218456 0.80 TLR7 (0.68) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6894165-B2 Imidazonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-17 US disclosed