Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035584 | 0.86 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDCHRNA7MAPTNPC1 | |
| SCHEMBL6035096 | 0.84 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDCHRNA7MAPTNPC1 | |
| SCHEMBL6035933 | 0.83 | GAA (0.36) | SMN1; SMN2HPGDGPR119CHRNA7MAPT | |
| SCHEMBL6036080 | 0.82 | SMN1; SMN2 (0.36) | SMN1; SMN2HPGDGPR119CHRNA7MAPT | |
| SCHEMBL6036156 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2HPGDCHRNA7MAPTNPC1 | |
| SCHEMBL6035509 | 0.79 | SMN1; SMN2 (0.37) | SMN1; SMN2HPGDCHRNA7MAPTNPC1 | |
| SCHEMBL6036282 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDMAPTGAANPC1 | |
| SCHEMBL6034663 | 0.77 | PPARG (0.44) | SMN1; SMN2HPGDGCGR | |
| SCHEMBL6035883 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2HPGDCHRNA7MAPTNPC1 | |
| SCHEMBL6035136 | 0.77 | PPARA (0.40) | SMN1; SMN2HPGDMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |