SCHEMBL628772

SCHEMBL628772

NC(=O)Cc1c(C=O)ccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 2/20 0.45
GLA P06280 1/20 0.45
HPGD P15428 1/20 0.45
ERN1 O75460 4/20 0.41
MAPT P10636 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
POLB P06746 2/20 0.38
PTPN1 P18031 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27516488 0.85 KDM4E (0.63) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL7840449 0.80 PTPN1 (0.51) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL23499977 0.78 KDM4E (0.72) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL2369777 0.77 KDM4E (0.47) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL4456627 0.77 KDM4E (0.47) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL29672837 0.77 KDM4E (0.47) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL4822278 0.76 ERN1 (0.46) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL3383364 0.76 ERN1 (0.42) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL12426752 0.76 NCEH1 (0.45) KDM4EGAAALDH1A1HSD17B10GLA
SCHEMBL7542805 0.75 MAPT (0.38) KDM4EGAAALDH1A1HSD17B10GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2036984-B1 Reversion of the negative selective effect of negative marker proteins as selection procedure BASF PLANT SCIENCE GMBH (DE) 2012-02-22 EP claimed
EP-2036984-A2 Reversion of the negative selective effect of negative marker proteins as selection procedure BASF Plant Science GmbH (DE) 2009-03-18 EP claimed
EP-1527183-B1 NOVEL SELECTION METHOD BASF PLANT SCIENCE GMBH (DE) 2008-08-20 EP claimed
US-20060218658-A1 Novel selection method BASF PLANT SCIENCE GMBH (DE) 2006-09-28 US claimed
US-20150368663-A1 METHOD FOR ISOLATION OF TRANSCRIPTION TERMINATION SEQUENCES BASF PLANT SCIENCE GMBH (DE) 2015-12-24 US disclosed
US-9133466-B2 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2015-09-15 US disclosed
EP-2074219-B1 NUCLEIC ACID SEQUENCES FOR REGULATION OF EMBRYO-SPECIFIC EXPRESSION IN MONOCOTYLEDONOUS PLANTS BASF PLANT SCIENCE GMBH (DE) 2013-11-20 EP disclosed
US-20130236954-A1 Method for Isolation of Transcription Termination Sequences BASF PLANT SCIENCE GMBH (DE) 2013-09-12 US disclosed
US-8465915-B2 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-06-18 US disclosed
EP-2166104-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-06-12 EP disclosed
EP-2166103-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-05-22 EP disclosed
EP-2163635-B1 Method for isolation of transcription termination sequences BASF PLANT SCIENCE GMBH (DE) 2013-05-22 EP disclosed
US-20070243543-A1 Method for Isolation of Transcription Termination Sequences BASF PLANT SCIENCE GMBH (DE) 2007-10-18 US disclosed
WO-2006133983-A1 STARCHY-ENDOSPERM AND/OR GERMINATING EMBRYO-SPECIFIC EXPRESSION IN MONO-COTYLEDONOUS PLANTS BASF PLANT SCIENCE GMBH (DE) 2006-12-21 WO disclosed
EP-1727907-A1 POST HARVEST CONTROL OF GENETICALLY MODIFIED CROP GROWTH EMPLOYING D-AMINO ACID COMPOUNDS BASF Plant Science GmbH (DE) 2006-12-06 EP disclosed
EP-1727906-A1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF Plant Science GmbH (DE) 2006-12-06 EP disclosed
WO-2005090581-A1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2005-09-29 WO disclosed
WO-2005090582-A1 POST HARVEST CONTROL OF GENETICALLY MODIFIED CROP GROWTH EMPLOYING D-AMINO ACID COMPOUNDS BASF PLANT SCIENCE GMBH (DE) 2005-09-29 WO disclosed
EP-1527183-A2 NOVEL SELECTION METHOD BASF Plant Science GmbH (DE) 2005-05-04 EP disclosed
WO-2004013333-A2 INVERSION OF THE NEGATIVE-SELECTIVE EFFECT OF NEGATIVE MARKER PROTEINS USING SELECTION METHODS BASF PLANT SCIENCE GMBH (DE) 2004-02-12 WO disclosed