Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774016 | 0.77 | ACP1 (0.52) | ACP1ALDH1A1HPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL4769537 | 0.76 | ACP1 (0.51) | ACP1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL29007301 | 0.74 | NPC1 (0.56) | ACP1RAB9ATDP1ALDH1A1HPGD | |
| SCHEMBL4772637 | 0.70 | NPC1 (0.49) | ACP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL14102727 | 0.70 | NPSR1 (0.47) | ACP1RAB9APOLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4763667 | 0.69 | NPC1 (0.48) | ACP1RAB9APOLBALDH1A1HPGD | |
| SCHEMBL4763566 | 0.69 | HRH3 (0.48) | ACP1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL4765212 | 0.69 | BCHE (0.49) | ACP1RAB9AALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL4763394 | 0.69 | NPSR1 (0.47) | ACP1RAB9APOLBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL4770729 | 0.68 | HRH3 (0.47) | ACP1RAB9AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |