SCHEMBL628863

SCHEMBL628863

O=C=C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775657 0.91
SCHEMBL28189502 0.70
SCHEMBL11216767 0.68
SCHEMBL9511438 0.67
Carbon Dioxide SCHEMBL9937404 0.67
SCHEMBL7454026 0.65
SCHEMBL7124848 0.63
Carbon Dioxide SCHEMBL15022477 0.63
SCHEMBL5163511 0.63
SCHEMBL5845463 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661475-B Preparation method of alpha-allyl-alpha, alpha-difluoro amide compound 南京工业大学 2026-04-17 CN disclosed
CN-119661475-A Preparation method of alpha-allyl-alpha, alpha-difluoro amide compound 南京工业大学 2025-03-21 CN disclosed
CN-119661475-A Preparation method of alpha-allyl-alpha, alpha-difluoro amide compound 南京工业大学 2025-03-21 CN disclosed
CN-117843519-A Preparation of difluoro ketene and method for converting difluoro ketene into difluoro acetate and difluoro acetate amide 南京工业大学 2024-04-09 CN disclosed
CN-117843519-A Preparation of difluoro ketene and method for converting difluoro ketene into difluoro acetate and difluoro acetate amide 南京工业大学 2024-04-09 CN disclosed
CN-117843519-A Preparation of difluoro ketene and method for converting difluoro ketene into difluoro acetate and difluoro acetate amide 南京工业大学 2024-04-09 CN disclosed
CN-117843543-A Preparation method of alpha, alpha-difluorobutyrolactam 南京工业大学 2024-04-09 CN disclosed
US-20240018381-A1 NANOIMPRINT LITHOGRAPHY RESIN COMPOSITION ILLUMINA, INC. 2024-01-18 US disclosed
WO-2023200753-A1 PERSONAL CARE COMPOSITION CONTAINING A BIOSURFACTANT THE PROCTER & GAMBLE COMPANY (US) 2023-10-19 WO disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 US disclosed
EP-1332143-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA Pharma AG (DE) 2003-08-06 EP disclosed
US-6384048-B1 GASTROINTESTINAL DISORDERS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2002-05-07 US disclosed
WO-2002034749-A1 POLYSUBSTITUTED IMIDAZOPYRIDINES AS GASTRIC SECRETION INHIBITORS ALTANA PHARMA AG (DE) 2002-05-02 WO disclosed
EP-1127059-A1 IMIDAZONAPHTHYRIDINES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 2001-08-29 EP disclosed
US-6197536-B1 DEPSIPEPTIDE WHICH IS SUBSTRATE OF HEPATITIS C VIRUS PROTEASE; FOR HIGH-THROUGH PUT SCREENING OF ENZYME INHIBITORS/VIRICIDES ISTITUTO DI RICERCHE DI BIOLOGIA MOLECULARE S.P.A. (IT) 2001-03-06 US disclosed
WO-2000026217-A1 IMIDAZONAPHTHYRIDINES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-05-11 WO disclosed
EP-0846164-A2 METHODOLOGY TO PRODUCE, PURIFY AND ASSAY POLYPEPTIDES WITH THE PROTEOLYTIC ACTIVITY OF THE HCV NS3 PROTEASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 1998-06-10 EP disclosed
WO-1997008304-A2 METHODOLOGY TO PRODUCE, PURIFY AND ASSAY POLYPEPTIDES WITH THE PROTEOLYTIC ACTIVITY OF THE HCV NS3 PROTEASE ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) 1997-03-06 WO disclosed
EP-0736302-A2 Protease inhibitors, a DNA construct for the expression of a protease and a process for measuring proteases and/or protease inhibitors Stichting REGA V.Z.W. (BE) 1996-10-09 EP disclosed
EP-0733369-A1 Protease inhibitors, a DNA construct for the expression of a protease and a process for measuring proteases and/or protease inhibitors Stichting REGA V.Z.W. (BE) 1996-09-25 EP disclosed