Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628923 | 1.00 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7874253 | 0.93 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL7908512 | 0.89 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL7908510 | 0.89 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL7867376 | 0.88 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL6628567 | 0.88 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL6625909 | 0.87 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7870223 | 0.87 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL6629271 | 0.84 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL628618 | 0.84 | FNTA (0.59) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| JP-2010100619-A | INHIBITOR OF PROTEIN ISOPRENYL TRANSFERASE | UNIV OF PITTSBURGH | 2010-05-06 | — | — | JP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |