Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629437 | 0.88 | AR (0.37) | ARPGRHDAC1 | |
| SCHEMBL14735662 | 0.83 | AR (0.39) | ARPGR | |
| SCHEMBL629084 | 0.82 | AR (0.47) | ARPGRHDAC1 | |
| SCHEMBL629347 | 0.81 | AR (0.42) | ARPGR | |
| SCHEMBL629295 | 0.79 | AR (0.44) | ARPGRHDAC1 | |
| SCHEMBL890673 | 0.78 | AR (0.40) | ARPGR | |
| Hydrochloric Acid SCHEMBL891225 | 0.78 | AR (0.44) | ARPGRHDAC1 | |
| SCHEMBL629446 | 0.77 | AR (0.46) | ARPGRHDAC1 | |
| SCHEMBL629334 | 0.76 | AR (0.38) | ARPGRHDAC1 | |
| SCHEMBL628972 | 0.76 | AR (0.50) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419410-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119193-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2010-10-21 | — | — | WO | disclosed |