SCHEMBL6290

SCHEMBL6290

O=Cc1ccc(-c2ccccn2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
LMNA P02545 4/20 0.50
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 2/20 0.50
CCR1 P32246 2/20 0.50
CCR5 P51681 2/20 0.50
CCR8 P51685 2/20 0.50
METAP1 P53582 2/20 0.50
POLB P06746 1/20 0.50
BLM P54132 1/20 0.50
HIF1A Q16665 1/20 0.50
DOHH Q9BU89 1/20 0.50
P4HTM Q9NXG6 1/20 0.50
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
ALDH1A1 P00352 4/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29443808 1.00 KDM4E (0.50) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL31631020 0.98 CYP2A6 (0.48) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL16381817 0.98 CYP2A6 (0.48) KDM4ELMNACYP1A2CYP2A6CCR1
Hydrazine SCHEMBL7944033 0.96 CA12 (0.50) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL29144944 0.93 CA12 (0.45) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL2625141 0.85 CYP2A6 (0.47) KDM4ELMNACYP1A2CYP2A6CCR1
Dipyridyl SCHEMBL29022230 0.84 KDM4E (0.47) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL31247782 0.83 CYP11B1 (0.40) KDM4ELMNACYP2A6CA12CA1
SCHEMBL31099420 0.83 CCR1 (0.50) KDM4ELMNACYP1A2CYP2A6CCR1
SCHEMBL28903052 0.83 ABL1 (0.46) KDM4ELMNACYP1A2CYP2A6CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 848 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101955-A Separator and method for producing same 上海恩捷新材料科技有限公司 2024-12-10 CN claimed
CN-118292192-A Composite nanofiber membrane, preparation method thereof and application thereof in agricultural pest control 华南农业大学 2024-07-05 CN claimed
CN-115974838-B Cyanine modified 2-phenylpyridine derivative, preparation method thereof and photocatalytic antibacterial application 中山大学 2024-05-31 CN claimed
CN-115960042-B 3- (dicyanomethylene) indene-1-ketone modified 2-phenylpyridine derivative, and preparation method and application thereof 中山大学 2024-03-29 CN claimed
CN-116987024-A Preparation method of atazanavir intermediate 浙江荣耀生物科技股份有限公司 2023-11-03 CN claimed
CN-116813672-A Iridium complex and preparation method and application thereof 东北师范大学 2023-09-29 CN claimed
CN-116570731-A Near infrared/glutathione dual-response nanocapsule integrating targeting, controllable drug delivery and photoacoustic imaging and preparation method thereof 清源创新实验室 2023-08-11 CN claimed
CN-114957105-B Dicarbonyl ligand and preparation method and application thereof 中山大学 2023-08-04 CN claimed
CN-116239759-A Conjugated two-dimensional polymer film and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2023-06-09 CN claimed
CN-112294956-B Iridium photosensitizer and preparation method and application thereof 中山大学 2023-05-05 CN claimed
CN-1678615-A Biaryl substituted diazabicycloalkanes as nicotinic acetylcholine antagonists ASTRAZENECA AB (SE) 2005-10-05 CN claimed
EP-1274684-B1 PROCESS FOR THE PREPARATION OF ARYL-PYRIDINYL COMPOUNDS EUTICALS PRIME EUROP THERAPEUT (IT) 2005-05-25 EP claimed
US-6765097-B1 Process for the preparation of aryl-pyridinyl compounds EUTICALS PRIME EUROPEAN THERAPEUTICAL SPA (IT) 2004-07-20 US claimed
EP-0979820-B1 2-Phenylpyridine derivatives and production method thereof SUMIKA FINE CHEMICALS CO LTD (JP) 2003-05-07 EP claimed
EP-1274684-A1 PROCESS FOR THE PREPARATION OF ARYL-PYRIDINYL COMPOUNDS Euticals Prime European Therapeutical S.P.A (IT) 2003-01-15 EP claimed
US-6268503-B1 REACTING 2-(4-BROMOMETHYLPHENYL)PYRIDINE SALT OR 2-(4-DIBROMOMETHYLPHENYL)PYRIDINE WITH HEXAMETHYLENETETRAMINE AND WATER TO PROVIDE 4-(PYRIDIN-2-YL)BENZALDEHYDE SUMIKA FINE CHEMICALS CO., LTD. (JP) 2001-07-31 US claimed
US-6242608-B1 REACTING 4-(PYRIDIN-2-YL)BENZALDEHYDE WITH HYDRAZINE TO FORM 4-(PYRIDIN-2-YL)BENZALDEHYDE HYDRAZONE; CHEMICAL INTERMEDIATE TO AN ANTI-HIV DRUG SUMIKA FINE CHEMICALS CO., LTD. (JP) 2001-06-05 US claimed
WO-2001027083-A1 PROCESS FOR THE PREPARATION OF ARYL-PYRIDINYL COMPOUNDS EUTICALS PRIME EUROPEAN THERAPEUTICAL SPA (IT) 2001-04-19 WO claimed
US-6147218-A 2-phenylpyridine derivative and production method thereof SUMIKA FINE CHEMICALS CO., LTD. (JP) 2000-11-14 US claimed
EP-0979820-A1 2-Phenylpyridine derivatives and production method thereof SUMIKA FINE CHEMICALS Co., Ltd. (JP) 2000-02-16 EP claimed