⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5249006 | 0.93 | EPHX1 (0.67) | — | |
| SCHEMBL6287268 | 0.92 | EPHX1 (0.55) | — | |
| SCHEMBL5246698 | 0.91 | EPHX1 (0.70) | — | |
| SCHEMBL21069905 | 0.91 | EPHX1 (0.70) | — | |
| SCHEMBL12172818 | 0.87 | EPHX1 (0.71) | — | |
| SCHEMBL14067802 | 0.85 | EPHX1 (0.83) | — | |
| SCHEMBL10817551 | 0.85 | EPHX1 (0.83) | — | |
| SCHEMBL10812052 | 0.85 | EPHX1 (0.83) | — | |
| SCHEMBL10812071 | 0.85 | EPHX1 (0.83) | — | |
| SCHEMBL10817110 | 0.85 | EPHX1 (0.83) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260055099-A1 | PROTACS FOR TARGETED DEGRADATION OF KAT2A AND KAT2B FOR THE TREATMENT OF CANCER | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2026-02-26 | — | — | US | disclosed |
| CN-114805139-B | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2023-10-20 | — | — | CN | disclosed |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| WO-2023196444-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20220289698-A1 | INHIBITORS OF HUMAN ATGL | Karl-Franzens-Universität Graz (AT) | 2022-09-15 | — | — | US | disclosed |
| CN-109715632-B | Macrocyclic indole derivatives | 拜尔公开股份有限公司 | 2021-10-26 | — | — | CN | disclosed |
| US-10696779-B2 | Silicon-containing compound, urethane resin, stretchable film, and method for forming the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| CN-105316669-B | A kind of stainless steel antibacterial passivating solution and preparation method thereof | 东莞市佳乾新材料科技有限公司 | 2017-11-03 | — | — | CN | disclosed |
| US-7619092-B2 | Piperidine compounds | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-11-17 | — | — | US | disclosed |
| US-6916854-B2 | Heat and/or light curable films or coatings comprising polyurethanes or polyureaurethane copolymers having storage stability, used as automobile paints | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-12 | — | — | US | disclosed |
| US-20040097642-A1 | Unsaturated compounds containing carbamate terminal groups or urea terminal groups | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-20 | — | — | US | disclosed |