⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL8513662 | 0.97 | — | — | |
| Butane SCHEMBL9135838 | 0.86 | MCL1 (0.37) | — | |
| SCHEMBL9768592 | 0.84 | — | — | |
| Biphenyl SCHEMBL7216507 | 0.80 | DHODH (0.46) | — | |
| SCHEMBL9483414 | 0.76 | — | — | |
| SCHEMBL2891916 | 0.74 | — | — | |
| Oxalic Acid SCHEMBL29351824 | 0.73 | KDM5B (0.42) | — | |
| SCHEMBL28190818 | 0.71 | — | — | |
| SCHEMBL9280703 | 0.71 | — | — | |
| SCHEMBL27480502 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023092175-A1 | NOVEL P2X7 RECEPTOR ANTAGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2023-06-01 | — | — | WO | claimed |
| CN-109053586-B | Production method of carbendazim | 安徽东至广信农化有限公司 | 2022-01-07 | — | — | CN | claimed |
| CN-104176724-A | Preparation method and product of nitrogen-doped carbon nano-tube | UNIV ZHEJIANG | 2014-12-03 | — | — | CN | claimed |
| CN-104085878-A | Surface functionalized ordered mesopore nitrogen-doped carbon material and preparation method thereof | UNIV ZHEJIANG | 2014-10-08 | — | — | CN | claimed |
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | claimed |
| EP-0934280-B1 | PDE IV INHIBITING 2-CYANOIMINOIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2003-04-09 | — | — | EP | claimed |
| EP-0704438-B1 | Process for the preparation of 2-cyanoiminothiazolidine | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 1998-02-11 | — | — | EP | claimed |
| EP-0695744-B1 | Process for the preparation of cyanimino-1,3-thiazolidine | BAYER AG (DE) | 1997-10-08 | — | — | EP | claimed |
| US-5574165-A | Process for the preparation of cyanoimino-1,3-thiazolidines | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | claimed |
| EP-0470050-B1 | Process for the preparation of 2-amino-4-alkoxy-s-triazines | CIBA GEIGY AG (CH) | 1995-11-02 | — | — | EP | claimed |
| EP-0371438-B1 | 3,5-Di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxiphenyl- 1,2,4-thiadiazoles, -oxadiazoles as antiinflammatory agents | WARNER LAMBERT CO (US) | 1995-08-30 | — | — | EP | claimed |
| EP-0523619-B1 | Process for the preparation of N-cyanimidocarbonates | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 1995-03-15 | — | — | EP | claimed |
| EP-0480939-B1 | HETEROCYCLIC AMINES HAVING CENTRAL NERVOUS SYSTEM ACTIVITY | UPJOHN CO (US) | 1995-01-25 | — | — | EP | claimed |
| US-5208351-A | PROCESS FOR THE PREPARATION OF N-CYANOIMIDOCARBONATES | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1993-05-04 | — | — | US | claimed |
| EP-0466710-A1 | [5(6)-(BENZISOXA-, BENZISOTHIA- OR INDAZOL-3-YL)-1H-BENZIMIDAZOL-2-YL] CARBAMATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-01-22 | — | — | EP | claimed |
| WO-1990010630-A1 | [5(6)-(BENZISOXA-, BENZISOTHIA- OR INDAZOL-3-YL)-1H-BENZIMIDAZOL-2-YL] CARBAMATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-09-20 | — | — | WO | claimed |
| EP-0387941-A1 | [5(6)-(benzisoxa-, benzisothia- or indazol-3-yl)-1H-benzimidazol-2-yl] carbamates | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-09-19 | — | — | EP | claimed |
| EP-0328203-A2 | [5(6) (1H-azole-1-ylmethyl)benzimidazole] carbamates | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-08-16 | — | — | EP | claimed |
| EP-0129832-B1 | PROCESS FOR THE REDUCTION OF THE FORMATION OF BY-PRODUCTS DURING THE PREPARATION OF CARBENDAZIM | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-19 | — | — | EP | claimed |
| EP-0146642-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2-(4-(FUROYL-2)-PIPERAZIN-1-YL)-QUINAZOLINE AND ITS PHYSIOLOGICALLY ACCEPTABLE SALT | LUDWIG HEUMANN & CO GMBH (DE) | 1988-01-20 | — | — | EP | claimed |