Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629001 | 1.00 | KDM4E (0.47) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL7236428 | 0.87 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6938057 | 0.87 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL11247741 | 0.87 | TSHR (0.58) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL7236663 | 0.85 | USP2 (0.60) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2929806 | 0.83 | USP2 (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL2244078 | 0.82 | TSHR (0.52) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL629087 | 0.80 | KDM4E (0.40) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL22673043 | 0.77 | TSHR (0.54) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL28098985 | 0.75 | TSHR (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419410-B1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA SAS (FR) | 2013-03-06 | — | — | EP | disclosed |
| EP-2419410-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119193-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2010-10-21 | — | — | WO | disclosed |