Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629236 | 1.00 | FGFR3 (0.70) | FGFR3KDR | |
| SCHEMBL557555 | 0.91 | FGFR3 (0.67) | FGFR3KDR | |
| SCHEMBL557556 | 0.91 | FGFR3 (0.67) | FGFR3KDR | |
| SCHEMBL556272 | 0.91 | FGFR3 (0.73) | FGFR3KDR | |
| SCHEMBL556273 | 0.91 | FGFR3 (0.73) | FGFR3KDR | |
| SCHEMBL557207 | 0.90 | FGFR3 (0.66) | FGFR3KDR | |
| SCHEMBL10265482 | 0.90 | FGFR3 (0.66) | FGFR3KDR | |
| SCHEMBL556723 | 0.90 | FGFR3 (0.68) | FGFR3KDR | |
| SCHEMBL556722 | 0.90 | FGFR3 (0.68) | FGFR3KDR | |
| SCHEMBL557526 | 0.90 | FGFR3 (0.85) | FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419427-A1 | BICYCLIC HETEROCYCLYL DERIVATIVES AS FGFR KINASE INHIBITORS FOR THERAPEUTIC USE | Astex Therapeutics Ltd. (GB) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010119284-A1 | BICYCLIC HETEROCYCLYL DERIVATIVES AS FGFR KINASE INHIBITORS FOR THERAPEUTIC USE | ASTEX THERAPEUTICS LIMITED (GB) | 2010-10-21 | — | — | WO | disclosed |