SCHEMBL6292397

SCHEMBL6292397

O=C(O)COCCCCN1C(=O)CCCC1/C=C/C(O)Cc1cccc(Cl)c1

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 15/20 0.70
PTGER2 P43116 3/20 0.61
PTGER3 P43115 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1377303 1.00 PTGER4 (0.70) PTGER4PTGER2PTGER3
SCHEMBL1377304 1.00 PTGER4 (0.70) PTGER4PTGER2PTGER3
SCHEMBL1377308 1.00 PTGER4 (0.70) PTGER4PTGER2PTGER3
SCHEMBL1377301 1.00 PTGER4 (0.70) PTGER4PTGER2PTGER3
SCHEMBL1035813 0.95 PTGER4 (0.78) PTGER4PTGER2PTGER3
SCHEMBL1035816 0.95 PTGER4 (0.78) PTGER4PTGER2PTGER3
SCHEMBL1035815 0.95 PTGER4 (0.78) PTGER4PTGER2PTGER3
SCHEMBL1035818 0.95 PTGER4 (0.78) PTGER4PTGER2PTGER3
SCHEMBL1377822 0.93 PTGER4 (0.60) PTGER4PTGER2PTGER3
SCHEMBL1377829 0.93 PTGER4 (0.60) PTGER4PTGER2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6977260-B2 administering to an animal having ocular hypertension a piperidynly analog; a container adapted to dispense the ophthalmic solution in a metered form ALLERGAN, INC. (US) 2005-12-20 US claimed