Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 1.00 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.54 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261354 | 1.00 | HRH3 (1.00) | HRH3DRD2DRD3TLR9TLR7 | |
| SCHEMBL5427098 | 0.91 | HRH3 (0.83) | HRH3DRD2DRD3TLR9TLR7 | |
| SCHEMBL6295832 | 0.90 | HRH3 (1.00) | HRH3DRD2DRD3TLR9TLR7 | |
| SCHEMBL5260036 | 0.90 | HRH3 (1.00) | HRH3DRD2DRD3TLR9TLR7 | |
| SCHEMBL4653816 | 0.87 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL6291771 | 0.87 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL5257756 | 0.85 | HRH3 (1.00) | HRH3DRD2DRD3 | |
| SCHEMBL5261465 | 0.84 | HRH3 (0.72) | HRH3DRD2DRD3 | |
| SCHEMBL5260918 | 0.84 | HRH3 (0.80) | HRH3DRD2DRD3 | |
| SCHEMBL5413761 | 0.81 | HRH3 (0.68) | HRH3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199117-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-7199117-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-6908929-B2 | Phenyl-substituted imidazopyridines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2005-06-21 | — | — | US | disclosed |