Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 16/20 | 0.69 |
| ▸ | HTR2C | P28335 | 16/20 | 0.69 |
| ▸ | HTR2B | P41595 | 15/20 | 0.69 |
| ▸ | PNMT | P11086 | 2/20 | 0.46 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094699 | 1.00 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL6298622 | 1.00 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTASIC3 | |
| SCHEMBL1094635 | 0.82 | HTR2A (1.00) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL6294060 | 0.82 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL1094636 | 0.82 | HTR2A (1.00) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL1094393 | 0.82 | HTR2A (1.00) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL1094601 | 0.82 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL6293734 | 0.82 | HTR2A (0.69) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL1095465 | 0.81 | HTR2C (1.00) | HTR2AHTR2CHTR2BPNMTADRA2A | |
| SCHEMBL1095893 | 0.81 | HTR2C (1.00) | HTR2AHTR2CHTR2BPNMTADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953787-B2 | 5HT2C receptor modulators | ARENA PHARMACEUTICALS, INC. (US) | 2005-10-11 | — | — | US | claimed |