Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4251857 | 0.87 | MAPT (0.43) | ALDH1A1MAPTABCC4LMNATSHR | |
| SCHEMBL6429282 | 0.87 | MAPT (0.43) | ALDH1A1MAPTABCC4LMNATSHR | |
| SCHEMBL6435481 | 0.86 | MAPT (0.42) | ALDH1A1MAPTABCC4LMNATSHR | |
| Hydrochloric Acid SCHEMBL2425645 | 0.86 | MAPT (0.42) | ALDH1A1MAPTABCC4LMNATSHR | |
| SCHEMBL30569316 | 0.83 | EPHX2 (0.49) | MAPTLMNAFAAHKMT2AATM | |
| SCHEMBL17939720 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2ACE2 | |
| SCHEMBL27905915 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2ACE2 | |
| SCHEMBL11800511 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2ACE2 | |
| SCHEMBL11796686 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2ACE2 | |
| SCHEMBL26122722 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041159-B8 | MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-02-22 | — | — | EP | disclosed |
| EP-2041159-B1 | MACROCYCLIC COMPOUNDS AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2011-09-28 | — | — | EP | disclosed |