Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.69 |
| ▸ | FNTB | P49356 | 1/20 | 0.69 |
| ▸ | BCHE | P06276 | 12/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192961 | 0.90 | FNTA (0.67) | FNTAFNTBBCHEACHE | |
| SCHEMBL6624997 | 0.85 | FNTA (0.52) | FNTAFNTBBCHEACHE | |
| SCHEMBL628888 | 0.83 | FNTA (0.51) | FNTAFNTBLTB4R2 | |
| SCHEMBL7869070 | 0.83 | BCHE (0.50) | FNTAFNTBBCHELTB4R2 | |
| SCHEMBL10192976 | 0.83 | FNTA (0.51) | FNTAFNTBLTB4R2 | |
| SCHEMBL629301 | 0.83 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL629302 | 0.83 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL7869137 | 0.83 | FNTA (0.51) | FNTAFNTBLTB4R2 | |
| SCHEMBL10193047 | 0.83 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL628947 | 0.80 | FNTA (0.87) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |